Effective support
starts with 
smart dosing 

Backed by clinical research, field trials, and real-world use with our own horses, we’ve developed targeted dosing guidelines for a wide range of situations. Whether you're seeking a natural alternative to pharmaceuticals or simply want to keep your horse comfortable and thriving during times of stress, we’ve got you covered!

Dosing Protocols by Condition or Situation

Title

Ulcers & Ulcer Symptoms

Days 1 - 14

Give your horse 1 ml per 100 lbs of body weight, both AM & PM.

Days 15 - 28

Give your horse 1 ml per 100 lbs of body weight once daily.

Maintenance

After the initial 28-day treatment, move to the maintenance dose of 0.5 ml per 100 lbs of body weight once daily.

Flare-ups

In the event that your horse experiences a flare-up, increase the dose to 1 ml per 100 lbs of body weight once daily, until symptoms subside.

Stressful Events

Prior to hauling, heavy work days, competition or weather changes, give 1 ml per 100 lbs of body weight once, at least an hour ahead of event. This additional dosage can be used in conjunction with the maintenance dose with no adverse effects.

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Title
Title

Older Horses & Hard Keepers

Days 1 - 10

Day 11 - Goal Weight Reached

Days 1 - 10

Maintenance

Once goal weight has been achieved, give 1 ml per 100 lbs of body weight 2 - 3 times per week.

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Title
Title

Horses in Rigorous Training

Days 1 - 14

Give your horse 1 ml per 100 lbs of body weight, both AM & PM.

Days 15 - 28

Give your horse 1 ml per 100 lbs of body weight once daily.

Maintenance

After the initial 28-day treatment, move to the maintenance dose of 0.5 ml per 100 lbs of body weight once daily.

Flare-ups

In the event that your horse experiences a flare-up, increase the dose to 1 ml per 100 lbs of body weight once daily, until symptoms subside.

Stressful Events

Prior to hauling, heavy work days, competition or weather changes, give 1 ml per 100 lbs of body weight once, at least an hour ahead of event. This additional dosage can be used in conjunction with the maintenance dose with no adverse effects.

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The standard Lorem

Title
Title

Respiratory Infections & Shipping Fever

Days 1 - Duration of Illness

Give your horse 1 ml per 100 lbs of body weight, once daily until symptoms (cough, nasal discharge, fever) subside.

In Conjuntion with Antibiotics

If antibiotics are being used, give 1 ml per 100 lbs of body weight, once daily for at least 10 days following the last dose of antibiotics. 

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The standard Lorem

Title
Title

Environmental Stress & Disease Outbreak

Prior to Changes in Weather or Disease Outbreak

Give your horse 1 ml per 100 lbs of body weight prior to weather changes or disease outbreak. 

Throughout Inclement Weather or Disease Outbreak

Continue to give at a rate of 1 ml per 100 lbs of body weight, once daily until weather regulates or danger of disease transmission has passed. 

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The standard Lorem

Title
Title

Colic & Colic Symptoms

At Onset of Colic

Give 30 to 50 ml orally at the onset of colic symptoms. A total of 100 ml may be used.

Persistent Colic Symptoms

PLEASE CONTACT YOUR VETERINARIAN IF COLIC SYMPTOMS PERSIST.

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Title

Hauling & New Environs

Day Before Departure - Return Home

All horses should receive 1 ml per 100 lbs orally the day before leaving and every
day while away from home.

Post-Return

If your horse is having difficulty settling back in upon returning home, give 1 ml per 100 lbs of body weigh once daily until behavior returns to normal.

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The standard Lorem

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Title

Foal Weaning

3 - 5 Days Prior to Weaning

Give both mare and foal 1 ml per 100 lbs orally 3 - 5 days before separation.

Day of Weaning and 3 - 5 Days After

Continue giving both mare and foal 1 ml per 100 lbs of body weigh once daily for 3 - 5 days after weaning. 

 

NOTE: Zesterra® is safe for pregnant and lactating mares. 

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The standard Lorem

Title
Title

Zesterra® is intended for oral use only in horses, donkeys and other equines. Safe for all ages and classes of horses, including pregnant or lactating mares.

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PHONE

1-800-254-0179

ADDRESS

PO Box 336
Aurora, SD 57002

EMAIL

orders@proearthanimalhealth.com

Pro Earth Animal Health

Every member of the Pro Earth team has a vested interest in animal health. As horse and cattle owners, we know first-hand the importance of keeping your animals healthy — whether you’re competing in the arena or counting pounds in the feedlot. This is your primary goal, and it’s ours, too. That is why we are committed to bringing you affordable, effective, all-natural products that deliver reliable, noticeable results.